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CLL Prognosis?

A MyLeukemiaTeam Member asked a question 💭
London, UK
July 20, 2024
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A MyLeukemiaTeam Member

The prognosis for Chronic Lymphocytic Leukemia (CLL) varies based on several factors:

- Age: Older age often leads to a worse prognosis
- Gene Changes: Specific gene mutations can affect the outlook.
- Protein Levels: High levels of ZAP-70, CD38, or beta-2 microglobulin in the blood can indicate a worse prognosis.
- Show Full Answer

The prognosis for Chronic Lymphocytic Leukemia (CLL) varies based on several factors:

- Age: Older age often leads to a worse prognosis.
- Gene Changes: Specific gene mutations can affect the outlook.
- Protein Levels: High levels of ZAP-70, CD38, or beta-2 microglobulin in the blood can indicate a worse prognosis.
- Lymphocyte Growth: Quickly growing lymphocytes or high numbers of prolymphocytes can lead to a worse prognosis.

The CLL International Prognostic Index (CLL-IPI) is used to estimate prognosis, considering factors like age, CLL stage, and gene mutations. The risk groups are:

- Low-risk: 93.2% live at least five years.
- Intermediate-risk: 79.3% live at least five years.
- High-risk: 63.3% live at least five years.
- Very high-risk: 23.3% live at least five years.

For more personalized information, it's best to consult with a doctor.

July 20, 2024

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