Is Anyone On An Obinutuxumab/Vanclexta Regimen For CLL? Anyone Have A Treatment-resistant Gene (q17)? If So, Please Share How It’s Going.
We need to stay positive and do what we can. 🙏🏻🙏🏻
I’m sorry to hear that. I have 6 months of monthly infusions (obinutiuxumab) and am now on 400 mg per day of Venclexta. I’ve had some dizziness, and I had a very low hemoglobin (5.9), which blood transfusions did not help. My hemoglobin is now 7.5 and my WBC has gone down, which is good. Apparently it’s a wait and see game for the next 30 days to hope for more improvements. I have hemolytic anemia too, and a splenectomy is one possibility if my red cells don’t improve. I B was diagnosed 14 years ago and have had four rounds of regular chemo (one of which gave me a 6 year remission. Now the q17 gene is showing up in over 90% of my cells, so that’s an added challenge. My prognosis has suffered but I have an oncologist I trust so it’s one month at a time (from blood test to blood test). Good luck to you!
Obinutuzumab and Venclexta (venetoclax) are used in combination to treat chronic lymphocytic leukemia (CLL). This combination can be particularly useful for people with certain genetic mutations, such as del(17p) or TP53 mutations, which make CLL more difficult to treat with traditional chemotherapy.
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I was on Venclexta before and during my chemo treatments . Once my Chemo treatments were concluded I was taken off Venclexta . I have defiantly had after effects either from the chemo and possibly the Venclexta . I have never been told by my Cancer team which after effects were caused by either one . I still have symptoms such as insomnia , headaches , severe loss of energy , and irregular bowel movements ,I also suffer from memory loss imbalance and a low apatite . .
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