Here are the key lab findings for diagnosing Chronic Lymphocytic Leukemia (CLL) based on my knowledge base:
1. Complete Blood Count (CBC):
- High Lymphocyte Count: A B lymphocyte count above 5,000 per microliter for at least three months is a main criterion for CLL diagnosis.
2. Immunophenotyping Tests
- Flow Show Full Answer
Here are the key lab findings for diagnosing Chronic Lymphocytic Leukemia (CLL) based on my knowledge base:
1. Complete Blood Count (CBC):
- High Lymphocyte Count: A B lymphocyte count above 5,000 per microliter for at least three months is a main criterion for CLL diagnosis.
2. Immunophenotyping Tests:
- Flow Cytometry: This test reads the proteins on the surface of leukemia cells to help identify CLL.
3. Microscopic Examination:
- Blood Cell Analysis: Examining blood cells under a microscope to identify abnormal cells.
4. Additional Blood Tests:
- Lactate Dehydrogenase (LDH): High levels may indicate disease presence.
- Beta-2 Microglobulin: Elevated levels can be a sign of cancer.
5. Bone Marrow Tests (occasionally used):
- Bone Marrow Biopsy: Removing a small sample of cells.
- Bone Marrow Aspiration: Removing fluid from inside the bone.
6. Cytogenetic Tests:
- Fluorescence In Situ Hybridization (FISH): Identifies gene abnormalities within CLL cells.
- Gene Mutation Tests: Detects specific mutations in leukemia cells.
7. Serum Immunoglobulin Tests:
- White Blood Cell Function: Determines if white blood cells are working correctly or are abnormal.
These lab findings help diagnose CLL, determine its severity, and guide treatment decisions. If you have any specific questions about these tests, feel free to ask!
November 6, 2024